APLP1 Antikörper (AA 360-440)

Produktnummer ABIN7217668

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch APLP1 in WB, ELISA und IHC (p). Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für APLP1 Antikörper (AA 360-440) (ABIN7217668)

Target: APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APLP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-APLP1 Antikörper

Bindungsspezifität: AA 360-440

Verwendungszweck: APLP-1 Polyclonal Antibody

Spezifität: APLP-1 Polyclonal Antibody detects endogenous levels of APLP-1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human APLP-1 at AA range: 360-440

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu APLP1

Target: APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))

Andere Bezeichnung: APLP-1

Hintergrund: Rabbit Anti-APLP-1 Polyclonal Antibody,APLP1, Amyloid-like protein 1, APLP, APLP-1,APLP1 encodes a member of the highly conserved amyloid precursor protein gene family. The amyloid-like protein 1 is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.,Amyloid-like protein 1

Gen-ID: 333

UniProt: P51693

Pathways: cAMP Metabolic Process