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ADRA2A Antikörper (AA 250-330)

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch ADRA2A in WB, ELISA und IF. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN7219826

Kurzübersicht für ADRA2A Antikörper (AA 250-330) (ABIN7219826)

Target

Alle ADRA2A Antikörper anzeigen
ADRA2A (Alpha-2A Adrenergic Receptor (ADRA2A))

Reaktivität

  • 42
  • 40
  • 24
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 59
  • 1
  • 1
Kaninchen

Klonalität

  • 60
  • 1
Polyklonal

Konjugat

  • 26
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ADRA2A Antikörper ist unkonjugiert

Applikation

  • 37
  • 18
  • 13
  • 13
  • 12
  • 10
  • 7
  • 5
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF)
  • Bindungsspezifität

    • 15
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 250-330

    Verwendungszweck

    AR-α2A Polyclonal Antibody

    Spezifität

    AR-α2A Polyclonal Antibody detects endogenous levels of AR-α2A protein.

    Aufreinigung

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    Immunogen

    Synthesized peptide derived from the Internal region of human AR-alpha2A at AA range: 250-330

    Isotyp

    IgG
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.

    Kommentare

    Primary Antibody

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • Target

    ADRA2A (Alpha-2A Adrenergic Receptor (ADRA2A))

    Andere Bezeichnung

    AR-alpha2A

    Hintergrund

    Rabbit Anti-AR-α2A Polyclonal Antibody,ADRA2A, ADRA2R, ADRAR, Alpha-2A adrenergic receptor, Alpha-2 adrenergic receptor subtype C10, Alpha-2A adrenoreceptor, Alpha-2A adrenoceptor, Alpha-2AAR,Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons, the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. ADRA2A encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences.,Alpha-2A adrenergic receptor

    Gen-ID

    150

    UniProt

    P08913

    Pathways

    EGFR Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Negative Regulation of Transporter Activity
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