ALDH1A2 Antikörper (AA 390-470)
Kurzübersicht für ALDH1A2 Antikörper (AA 390-470) (ABIN7225686)
Target
Alle ALDH1A2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 390-470
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Verwendungszweck
- Rabbit Anti-ALDH1A2 Polyclonal Antibody
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Spezifität
- ALDH1A2 Polyclonal Antibody detects endogenous levels of ALDH1A2 protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Synthesized peptide derived from the C-terminal region of human ALDH1A2 at AA range: 390-470
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC:1:50-300,ELISA 1:20000,IF 1:50-200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Haltbarkeit
- 12 months
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- ALDH1A2 (Aldehyde Dehydrogenase 1 Family, Member A2 (ALDH1A2))
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Andere Bezeichnung
- ALDH1A2
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Hintergrund
- ALDH1A2, RALDH2, Retinal dehydrogenase 2, RALDH 2, RalDH2, Aldehyde dehydrogenase family 1 member A2, Retinaldehyde-specific dehydrogenase type 2, RALDH(II)This protein ALDH1A2 belongs to the aldehyde dehydrogenase family of proteins. The product of ALDH1A2 (aldehyde dehydrogenase 1 family member A2) is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for ALDH1A2.
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Molekulargewicht
- 52kD
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Gen-ID
- 8854
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UniProt
- O94788
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Pathways
- Retinoic Acid Receptor Signaling Pathway
Target
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