AGXT2 Antikörper (AA 340-420)

Produktnummer ABIN7227242

Der Kaninchen Polyklonal anti-AGXT2 Antikörper wird verwendet zum Nachweis von AGXT2 in Proben von Human, Maus und Ratte. Er wurde validiert für WB und ELISA.

Kurzübersicht für AGXT2 Antikörper (AA 340-420) (ABIN7227242)

Target: AGXT2 (Alanine Glyoxylate Aminotransferase 2 (AGXT2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AGXT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-AGXT2 Antikörper

Bindungsspezifität: AA 340-420

Verwendungszweck: Rabbit Anti-AGT2 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of AGT2 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human AGT2 protein at AA range: 340-420

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu AGXT2

Target: AGXT2 (Alanine Glyoxylate Aminotransferase 2 (AGXT2))

Andere Bezeichnung: AGT2

Hintergrund: Alanine--glyoxylate aminotransferase 2, mitochondrial, AGT 2, (R)-3-amino-2methylpropionate--pyruvate transaminase, Beta-ALAAT II, Beta-alanine-pyruvate aminotransferase, D-AIBATThe protein encoded by AGXT2 is a class III pyridoxal-phosphate-dependent mitochondrial aminotransferase. It catalyzes the conversion of glyoxylate to glycine using L-alanine as the amino donor. It is an important regulator of methylarginines and is involved in the control of blood pressure in kidney. Polymorphisms in AGXT2 affect methylarginine and beta-aminoisobutyrate metabolism, and are associated with carotid atherosclerosis. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 56kD

Gen-ID: 64902

UniProt: Q9BYV1

Pathways: Monocarboxylic Acid Catabolic Process