AGRN Antikörper (AA 1900-1980)

Produktnummer ABIN7227240

Der Kaninchen Polyklonal Anti-AGRN Antikörper wurde für WB und ELISA validiert. Er ist geeignet, AGRN in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für AGRN Antikörper (AA 1900-1980) (ABIN7227240)

Target: AGRN (Agrin (AGRN))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AGRN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-AGRN Antikörper

Bindungsspezifität: AA 1900-1980

Verwendungszweck: AGRIN Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of AGRIN protein

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human AGRIN protein at AA range: 1900-1980

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu AGRN

Target: AGRN (Agrin (AGRN))

Andere Bezeichnung: AGRIN

Hintergrund: Rabbit Anti-AGRIN Polyclonal Antibody,Agrin, Agrin N-terminal 110 kDa subunit, Agrin C-terminal 110 kDa subunit, Agrin C-terminal 90 kDa fragment, C90, Agrin C-terminal 22 kDa fragment, C22,AGRN encodes one of several proteins that are critical in the development of the neuromuscular junction (NMJ), as identified in mouse knock-out studies. The encoded protein contains several laminin G, Kazal type serine protease inhibitor, and epidermal growth factor domains. Additional post-translational modifications occur to add glycosaminoglycans and disulfide bonds. In one family with congenital myasthenic syndrome affecting limb-girdle muscles, a mutation in AGRN was found. Alternative splicing results in multiple transcript variants encoding different isoforms.,AGRIN

Gen-ID: 375790

UniProt: O00468

Pathways: Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development