ADNP Antikörper (AA 80-160)

Produktnummer ABIN7220706

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ADNP in WB, ELISA, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für ADNP Antikörper (AA 80-160) (ABIN7220706)

Target: ADNP (Activity-Dependent Neuroprotector Homeobox (ADNP))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADNP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-ADNP Antikörper

Bindungsspezifität: AA 80-160

Verwendungszweck: Rabbit Anti-ADNP Polyclonal Antibody

Spezifität: ADNP Polyclonal Antibody detects endogenous levels of ADNP protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human ADNP at AA range: 80-160

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu ADNP

Target: ADNP (Activity-Dependent Neuroprotector Homeobox (ADNP))

Andere Bezeichnung: ADNP

Hintergrund: ADNP, ADNP1, KIAA0784, Activity-dependent neuroprotector homeobox protein, Activity-dependent neuroprotective proteinVasoactive intestinal peptide is a neuroprotective factor that has a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. ADNP encodes activity dependent neuroprotector homeobox that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. This gene is also upregulated in normal proliferative tissues. Finally, the encoded protein may increase the viability of certain cell types through modulation of p53 activity. Alternatively spliced transcript variants encoding the same protein have been described.

Molekulargewicht: 124kD

Gen-ID: 23394

UniProt: Q9H2P0

Pathways: Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process