ADCK5 Antikörper (AA 120-200)

Produktnummer ABIN7213488

Der Kaninchen Polyklonal anti-ADCK5 Antikörper wird verwendet zum Nachweis von ADCK5 in Proben von Human und Maus. Er wurde validiert für WB, ELISA und IF.

Kurzübersicht für ADCK5 Antikörper (AA 120-200) (ABIN7213488)

Target: ADCK5 (AarF Domain Containing Kinase 5 (ADCK5))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADCK5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-ADCK5 Antikörper

Bindungsspezifität: AA 120-200

Verwendungszweck: Rabbit Anti-ADCK5 Polyclonal Antibody

Spezifität: ADCK5 Polyclonal Antibody detects endogenous levels of ADCK5 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human ADCK5 at AA range: 120-200

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu ADCK5

Target: ADCK5 (AarF Domain Containing Kinase 5 (ADCK5))

Andere Bezeichnung: ADCK5

Hintergrund: ADCK5, Uncharacterized aarF domain-containing protein kinase 5CABC1 (chaperone activity of bc1 complex-like), also known as COQ8 or ADCK3 (aarF domain-containing protein kinase 3) is a 647 amino acid mitochondrial protein that belongs to the ADCK protein kinase. Ubiquitously expressed with higher expression in heart and skeletal muscle, CABC1 is thought to function as a chaperone in the proper assembly of protein complexes found in the respiratory chain. CABC1 expression is induced both in response to DNA damage and by the tumor suppressor p53. When CABC1 expression is inhibited, p53-induced apoptosis is partially suppressed, suggesting a possible role for CABC1 in tumor suppression. Mutations in the gene encoding CABC1 may be implicated in ubiquinone deficiency which can lead to cerebellar ataxia and seizures. Four isoforms of CABC1 exist due to alternative splicing events. Other members of the ADCK protein kinase family include ADCK1, ADCK2, ADCK4 and ADCK5.

Molekulargewicht: 66kD

Gen-ID: 203054

UniProt: Q3MIX3