ADCK1 Antikörper (AA 220-300)

Produktnummer ABIN7213484

Der Kaninchen Polyklonal Anti-ADCK1 Antikörper wurde für WB, ELISA, IF und IHC (p) validiert. Er ist geeignet, ADCK1 in Proben von Human und Maus zu detektieren.

Kurzübersicht für ADCK1 Antikörper (AA 220-300) (ABIN7213484)

Target: ADCK1 (AarF Domain Containing Kinase 1 (ADCK1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADCK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-ADCK1 Antikörper

Bindungsspezifität: AA 220-300

Verwendungszweck: ADCK1 Polyclonal Antibody

Spezifität: ADCK1 Polyclonal Antibody detects endogenous levels of ADCK1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human ADCK1 at AA range: 220-300

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu ADCK1

Target: ADCK1 (AarF Domain Containing Kinase 1 (ADCK1))

Andere Bezeichnung: ADCK1

Hintergrund: Rabbit Anti-ADCK1 Polyclonal Antibody,ADCK1, Uncharacterized aarF domain-containing protein kinase 1,CABC1 (chaperone activity of bc1 complex-like), also known as COQ8 or ADCK3 (aarF domain-containing protein kinase 3) is a 647 amino acid mitochondrial protein that belongs to the ADCK protein kinase. Ubiquitously expressed with higher expression in heart and skeletal muscle, CABC1 is thought to function as a chaperone in the proper assembly of protein complexes found in the respiratory chain. CABC1 expression is induced both in response to DNA damage and by the tumor suppressor p53. When CABC1 expression is inhibited, p53-induced apoptosis is partially suppressed, suggesting a possible role for CABC1 in tumor suppression. Mutations in the gene encoding CABC1 may be implicated in ubiquinone deficiency which can lead to cerebellar ataxia and seizures. Four isoforms of CABC1 exist due to alternative splicing events. Other members of the ADCK protein kinase family include ADCK1, ADCK2, ADCK4 and ADCK5.,Uncharacterized aarF domain-containing protein kinase 1

Gen-ID: 57143

UniProt: Q86TW2