XRN1 Antikörper

Produktnummer ABIN7232190

Dieser Anti-XRN1 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von XRN1 in WB und ELISA. Geeignet für Human und Maus.

Kurzübersicht für XRN1 Antikörper (ABIN7232190)

Target: XRN1 (5'-3' Exoribonuclease 1 (XRN1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser XRN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-XRN1 Antikörper

Verwendungszweck: XRN1 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of XRN1 protein

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human XRN1 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu XRN1

Target: XRN1 (5'-3' Exoribonuclease 1 (XRN1))

Andere Bezeichnung: XRN1

Hintergrund: Rabbit Anti-XRN1 Polyclonal Antibody,5'-3' exoribonuclease 1, Strand-exchange protein 1 homolog,XRN1 encodes a member of the 5'-3' exonuclease family. The encoded protein may be involved in replication-dependent histone mRNA degradation, and interacts directly with the enhancer of mRNA-decapping protein 4. In addition to mRNA metabolism, a similar protein in yeast has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly. Mutations in this gene are associated with osteosarcoma, suggesting that the encoded protein may also play a role in bone formation. Alternative splicing results in multiple transcript variants.,XRN1

Molekulargewicht: observerd band 187kDa

Gen-ID: 54464

UniProt: Q8IZH2