Rekombinanter ErbB2/Her2 (Pertuzumab Biosimilar) Antikörper

Produktnummer ABIN7200658

Dieses Anti-ErbB2/Her2 (Pertuzumab Biosimilar)-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von ErbB2/Her2 (Pertuzumab Biosimilar) in FACS und in vivo. Geeignet für Human.

Kurzübersicht für Rekombinanter ErbB2/Her2 (Pertuzumab Biosimilar) Antikörper (ABIN7200658)

Target: ErbB2/Her2 (Pertuzumab Biosimilar)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ErbB2/Her2 (Pertuzumab Biosimilar) Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), In vivo Studies (in vivo)

Produktdetails anti-ErbB2/Her2 (Pertuzumab Biosimilar) Antikörper

Verwendungszweck: Pertuzumab Biosimilar, Human HER2 Monoclonal Antibody

Spezifität: The monoclonal antibody pertuzumab biosimilar specifically binds to the human HER2/ErbB-2/c-neu.

Produktmerkmale: Recombinant humanized IgG1 Monoclonal Antibody.

Aufreinigung: Protein A affinity column

Reinheit: > 95% by SDS-PAGE under reducing conditions and HPLC.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: < 1 EU per 1 mg of the protein by the LAL method.

Immunogen: The monoclonal antibody pertuzumab biosimilar was produced in the pertuzumab biosimilar CHO stable cell line.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by pertuzumab.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, no stabilizers or preservatives.

Konservierungsmittel: Without preservative

Handhabung: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: 12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied.

Haltbarkeit: 12 months

Details zu ErbB2/Her2 (Pertuzumab Biosimilar)

Target: ErbB2/Her2 (Pertuzumab Biosimilar)

Substanzklasse: Biosimilar

Hintergrund: Pertuzumab, a humanized monoclonal antibody, inhibits HER dimerization and is used for the treatment of HER2-positive metastatic breast cancer, in combination with trastuzumab and docetaxel. By binding to HER2, Pertuzumab inhibits the dimerization of HER2 with other HER receptors, resulting in slowed tumor growth.