Rekombinanter TNFSF11 (Denosumab Biosimilar) Antikörper
Kurzübersicht für Rekombinanter TNFSF11 (Denosumab Biosimilar) Antikörper (ABIN7200656)
Target
Antikörpertyp
Fragment
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
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Verwendungszweck
- Denosumab Biosimilar, Human RANKL Monoclonal Antibody
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Spezifität
- The monoclonal antibody denosumab biosimilar specifically binds to the human RANKL (RANK ligand) protein.
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Produktmerkmale
- Denosumab, a fully human monoclonal antibody, inhibits the RANKL (RANK ligand) protein, the primary signal for bone removal. Denosumab can be used for the treatment of osteoporosis, treatment-induced bone loss, bone metastases, multiple myeloma, and giant cell tumor of bone.
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Aufreinigung
- Protein A or G affinity column
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Reinheit
- >95 % by reducing SDS-PAGE
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Sterilität
- 0.2 μm filtered
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Endotoxin-Niveau
- < 1 EU per 1 mg of the protein by the LAL method
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Immunogen
- The monoclonal antibody denosumab biosimilar was produced in the denosumab biosimilar CHO stable cell line.
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Isotyp
- IgG2
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Applikationshinweise
- ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by denosumab.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- > 3 mg/mL
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Buffer
- PBS, pH 7.4, no stabilizers or preservatives.
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Konservierungsmittel
- Without preservative
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Lagerung
- 4°C,-20 °C
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Informationen zur Lagerung
- 12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied.
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Haltbarkeit
- 12 months
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- TNFSF11 (Denosumab Biosimilar)
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Andere Bezeichnung
- Denosumab Biosimilar
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Substanzklasse
- Biosimilar
Target
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