Dieser Maus Monoklonal Antikörper erkennt spezifisch TNFSF11 (Denosumab Biosimilar) in FACS und in vivo. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN7200656
Kurzübersicht für Rekombinanter TNFSF11 (Denosumab Biosimilar) Antikörper (ABIN7200656)
Target
TNFSF11 (Denosumab Biosimilar)
Antikörpertyp
Recombinant Antibody
Fragment
Fab fragment
Reaktivität
Human
Wirt
Maus
Klonalität
Monoklonal
Konjugat
Dieser TNFSF11 (Denosumab Biosimilar) Antikörper ist unkonjugiert
Applikation
Flow Cytometry (FACS), In vivo Studies (in vivo)
Güteklasse
Research Grade
Verwendungszweck
Denosumab Biosimilar, Human RANKL Monoclonal Antibody
Spezifität
The monoclonal antibody denosumab biosimilar specifically binds to the human RANKL (RANK ligand) protein.
Produktmerkmale
Denosumab, a fully human monoclonal antibody, inhibits the RANKL (RANK ligand) protein, the primary signal for bone removal. Denosumab can be used for the treatment of osteoporosis, treatment-induced bone loss, bone metastases, multiple myeloma, and giant cell tumor of bone.
Aufreinigung
Protein A or G affinity column
Reinheit
>95 % by reducing SDS-PAGE
Sterilität
0.2 μm filtered
Endotoxin-Niveau
< 1 EU per 1 mg of the protein by the LAL method
Immunogen
The monoclonal antibody denosumab biosimilar was produced in the denosumab biosimilar CHO stable cell line.
Research Grade
Reaktivität: Human
Wirt: Mammalian Cells
Monoclonal
unconjugated
Recombinant Antibody
Applikationshinweise
ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by denosumab.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
> 3 mg/mL
Buffer
PBS, pH 7.4, no stabilizers or preservatives.
Konservierungsmittel
Without preservative
Lagerung
4°C,-20 °C
Informationen zur Lagerung
12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied.