Rekombinanter VEGF (Bevacizumab Biosimilar) Antikörper
Kurzübersicht für Rekombinanter VEGF (Bevacizumab Biosimilar) Antikörper (ABIN7200653)
Target
Antikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
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Verwendungszweck
- Bevacizumab Biosimilar, Human VEGF Monoclonal Antibody
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Spezifität
- The monoclonal antibody Bevacizumab biosimilar specifically binds to the human VEGF-A.
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Produktmerkmale
- Bevacizumab, the humanized anti-VEGF-A monoclonal antibody, produces angiogenesis inhibition and slows the growth of new blood vessels. As the first clinically available angiogenesis inhibitor in the United States, Bevacizumab is used for treatment of certain metastatic cancers, certain lung cancers, renal cancers, ovarian cancers, breast cancers, and glioblastoma multiforme of the brain. Vascular endothelial growth factor A (VEGF-A) stimulates angiogenesis in a variety of cancers, including colorectal, lung, breast, glioblastoma, kidney, and ovarian cancers.
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Aufreinigung
- Protein A or G affinity column
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Reinheit
- >95 % by reducing SDS-PAGE
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Sterilität
- 0.2 μm filtered
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Endotoxin-Niveau
- < 1 EU per 1 mg of the protein by the LAL method
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Immunogen
- The monoclonal antibody Bevacizumab biosimilar was produced in the bevacizumab biosimilar CHO stable cell line.
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Isotyp
- IgG1
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Applikationshinweise
- ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by bevacizumab.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- > 3 mg/mL
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Buffer
- PBS, pH 7.4, no stabilizers or preservatives.
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Konservierungsmittel
- Without preservative
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Lagerung
- 4°C,-20 °C
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Informationen zur Lagerung
- 12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied.
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Haltbarkeit
- 12 months
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- VEGF (Bevacizumab Biosimilar)
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Andere Bezeichnung
- Bevacizumab Biosimilar
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Substanzklasse
- Biosimilar
Target
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