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Rekombinanter VEGF (Bevacizumab Biosimilar) Antikörper

Reaktivität: Human FACS, in vivo Wirt: Maus Monoclonal unconjugated Recombinant Antibody
Produktnummer ABIN7200653
  • Target Alle VEGF (Bevacizumab Biosimilar) Produkte
    VEGF (Bevacizumab Biosimilar)
    Antikörpertyp
    Recombinant Antibody
    Reaktivität
    Human
    Wirt
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus
    Klonalität
    • 3
    • 2
    Monoklonal
    Konjugat
    • 5
    Dieser VEGF (Bevacizumab Biosimilar) Antikörper ist unkonjugiert
    Applikation
    • 4
    • 3
    • 3
    • 3
    • 3
    Flow Cytometry (FACS), In vivo Studies (in vivo)
    Verwendungszweck
    Bevacizumab Biosimilar, Human VEGF Monoclonal Antibody
    Spezifität
    The monoclonal antibody Bevacizumab biosimilar specifically binds to the human VEGF-A.
    Produktmerkmale
    Recombinant Humanized IgG1 Monoclonal Antibody generated from the same parent mouse antibody as ranibizumab.
    Aufreinigung
    Protein A affinity column
    Reinheit
    > 95% by SDS-PAGE under reducing conditions and HPLC.
    Sterilität
    0.2 μm filtered
    Endotoxin-Niveau
    < 1 EU per 1 mg of the protein by the LAL method.
    Immunogen
    The monoclonal antibody Bevacizumab biosimilar was produced in the bevacizumab biosimilar CHO stable cell line.
    Isotyp
    IgG1 kappa
  • Applikationshinweise
    ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by bevacizumab.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS, pH 7.4, no stabilizers or preservatives.
    Konservierungsmittel
    Without preservative
    Handhabung
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied.
    Haltbarkeit
    12 months
  • Target
    VEGF (Bevacizumab Biosimilar)
    Abstract
    VEGF (Bevacizumab Biosimilar) Produkte
    Synonyme
    MVCD1 antikoerper, VEGF antikoerper, VPF antikoerper, vascular endothelial growth factor A antikoerper, VEGFA antikoerper
    Substanzklasse
    Biosimilar
    Hintergrund
    Bevacizumab, the humanized anti-VEGF-A monoclonal antibody, produces angiogenesis inhibition and slows the growth of new blood vessels. As the first clinically available angiogenesis inhibitor in the United States, Bevacizumab is used for treatment of certain metastatic cancers, certain lung cancers, renal cancers, ovarian cancers, breast cancers, and glioblastoma multiforme of the brain.

    Vascular endothelial growth factor A (VEGF-A) stimulates angiogenesis in a variety of cancers, including colorectal, lung, breast, glioblastoma, kidney, and ovarian cancers.
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