SMYD2A Antikörper

Produktnummer ABIN715571

Der Kaninchen Polyklonal Anti-SMYD2A-Antikörper wurde für WB, IF (p) und IHC (p) validiert. Er ist geeignet, SMYD2A in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für SMYD2A Antikörper (ABIN715571)

Target: SMYD2A (SET and MYND Domain Containing 2a (SMYD2A))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMYD2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-SMYD2A Antikörper

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SMYD2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C

Haltbarkeit: 12 months

Details zu SMYD2A

Target: SMYD2A (SET and MYND Domain Containing 2a (SMYD2A))

Andere Bezeichnung: SMYD2

Hintergrund:

Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Has also methyltransferase activity toward non-histone proteins such as p53/TP53 and RB1. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates 'Lys-860' of RB1/RB.

Synonyms: HSKM B, HSKM-B, HSKMB, Histone methyltransferase SMYD2, HSKM-B, Lysine N-methyltransferase 3C, MGC119305, N lysine methyltransferase SMYD2, N-lysine methyltransferase SMYD2, SET and MYND domain containing 2, SET and MYND domain containing protein 2, SET and MYND domain-containing protein 2, Smyd2, SMYD2_HUMAN, Zinc finger MYND domain containing 14, ZMYND14.

Gen-ID: 56950