Integrin beta 7 Antikörper (AA 20-174)

Produktnummer ABIN7193968

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Integrin beta 7 in ELISA, IHC, FACS und ICC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Integrin beta 7 Antikörper (AA 20-174) (ABIN7193968)

Target: Integrin beta 7 (ITGB7)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Integrin beta 7 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Klon: 4C5D2

Produktdetails anti-Integrin beta 7 Antikörper

Bindungsspezifität: AA 20-174

Verwendungszweck: ITGB7 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human ITGB7 (AA: 20-174) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/50 - 1/200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu Integrin beta 7

Target: Integrin beta 7 (ITGB7)

Andere Bezeichnung: ITGB7

Hintergrund:

This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms dimers with an alpha4 chain or an alphaE chain and plays a role in leukocyte adhesion. Dimerization with alpha4 forms a homing receptor for migration of lymphocytes to the intestinal mucosa and Peyer's patches. Dimerization with alphaE permits binding to the ligand epithelial cadherin, a calcium-dependent adhesion molecule. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

Molekulargewicht: 86.9 kDa

Gen-ID: 3695

UniProt: P26010

Pathways: Integrin Complex