CXCR6 Antikörper

Produktnummer ABIN7193912

Produktdetails anti-CXCR6 Antikörper

Target: CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CXCR6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human CD186 expressed in E. coli.

Klon: 2A4D10

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB:1:500 - 1:2000, FCM:1:200 - 1:400, ELISA:1:10000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Details zu CXCR6

Target: CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))

Andere Bezeichnung: CD186 (CXCR6 Produkte)

Synonyme: BONZO antikoerper, CD186 antikoerper, STRL33 antikoerper, TYMSTR antikoerper, BB217514 antikoerper, C-X-C motif chemokine receptor 6 antikoerper, chemokine (C-X-C motif) receptor 6 L homeolog antikoerper, chemokine (C-X-C motif) receptor 6 antikoerper, CXCR6 antikoerper, cxcr6.L antikoerper, Cxcr6 antikoerper

Hintergrund:

Description: The protein encoded by this gene is a G protein-coupled receptor with seven transmembrane domains that belongs to the CXC chemokine receptor family. This family also includes CXCR1, CXCR2, CXCR3, CXCR4, CXCR5, and CXCR7. This gene, which maps to the chemokine receptor gene cluster, is expressed in several T lymphocyte subsets and bone marrow stromal cells. The encoded protein and its exclusive ligand, chemokine ligand 16 (CCL16), are part of a signalling pathway that regulates T lymphocyte migration to various peripheral tissues (the liver, spleen red pulp, intestine, lungs, and skin) and promotes cell-cell interaction with dendritic cells and fibroblastic reticular cells. CXCR6/CCL16 also controls the localization of resident memory T lymphocytes to different compartments of the lung and maintains airway resident memory T lymphocytes, which are an important first line of defense against respiratory pathogens. The encoded protein serves as an entry coreceptor used by HIV-1 and SIV to enter target cells, in conjunction with CD4.

Aliases: CXCR6, BONZO, CDw186, STRL33, TYMSTR

Molekulargewicht: 39.3 kDa

Gen-ID: 10663