NUP98 Antikörper (AA 1-218)

Produktnummer ABIN7193802

Produktdetails anti-NUP98 Antikörper

Target: NUP98 (Nucleoporin 98kDa (NUP98))

Bindungsspezifität: AA 1-218

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NUP98 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human NUP98 (AA: 1-218) expressed in E. coli.

Klon: 3G8C7

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB:1:500 - 1:2000, ICC:1:200 - 1:1000, FCM:1:200 - 1:400, ELISA:1:10000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Details zu NUP98

Target: NUP98 (Nucleoporin 98kDa (NUP98))

Andere Bezeichnung: NUP98 (NUP98 Produkte)

Synonyme: CG10198 antikoerper, CG10201 antikoerper, Dmel\\CG10198 antikoerper, Nup 96 antikoerper, Nup 98 antikoerper, Nup-98 antikoerper, Nup96 antikoerper, Nup98 antikoerper, Nup98-Nup96 antikoerper, Nup98/96 antikoerper, l(3)95BCd antikoerper, nup145 antikoerper, nup98-96 antikoerper, GB12688 antikoerper, NUP98 antikoerper, 4732457F17 antikoerper, AI849286 antikoerper, im:7151238 antikoerper, zgc:113968 antikoerper, zgc:63593 antikoerper, ADIR2 antikoerper, NUP196 antikoerper, NUP96 antikoerper, Nucleoporin 98-96kD antikoerper, nuclear pore complex protein Nup98-Nup96 antikoerper, nucleoporin 98 antikoerper, nucleoporin 98kDa antikoerper, nucleoporin 98 L homeolog antikoerper, Nup98-96 antikoerper, LOC408335 antikoerper, NUP98 antikoerper, LOC587580 antikoerper, Nup98 antikoerper, nup98 antikoerper, nup98.L antikoerper

Hintergrund:

Description: Nuclear pore complexes (NPCs) regulate the transport of macromolecules between the nucleus and cytoplasm, and are composed of many polypeptide subunits, many of which belong to the nucleoporin family. This gene belongs to the nucleoporin gene family and encodes a 186 kDa precursor protein that undergoes autoproteolytic cleavage to generate a 98 kDa nucleoporin and 96 kDa nucleoporin. The 98 kDa nucleoporin contains a Gly-Leu-Phe-Gly (GLGF) repeat domain and participates in many cellular processes, including nuclear import, nuclear export, mitotic progression, and regulation of gene expression. The 96 kDa nucleoporin is a scaffold component of the NPC. Proteolytic cleavage is important for targeting of the proteins to the NPC. Translocations between this gene and many other partner genes have been observed in different leukemias. Rearrangements typically result in chimeras with the N-terminal GLGF domain of this gene to the C-terminus of the partner gene. Alternative splicing results in multiple transcript variants encoding different isoforms, at least two of which are proteolytically processed. Some variants lack the region that encodes the 96 kDa nucleoporin.

Aliases: ADIR2, NUP96, NUP196, Nup98-96

Molekulargewicht: 197.5 kDa

Gen-ID: 4928

Pathways: Stem Cell Maintenance, Protein targeting to Nucleus, SARS-CoV-2 Protein Interaktom