L1CAM Antikörper (AA 20-197)

Produktnummer ABIN7193538

Dieses Anti-L1CAM-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von L1CAM in FACS und ELISA. Geeignet für Human.

Kurzübersicht für L1CAM Antikörper (AA 20-197) (ABIN7193538)

Target: L1CAM (L1 Cell Adhesion Molecule (L1CAM))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser L1CAM Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), ELISA

Klon: 5C6A10

Produktdetails anti-L1CAM Antikörper

Bindungsspezifität: AA 20-197

Verwendungszweck: CD171 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human CD171 (AA: 20-197) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu L1CAM

Target: L1CAM (L1 Cell Adhesion Molecule (L1CAM))

Andere Bezeichnung: CD171

Hintergrund:

The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons.

Molekulargewicht: 140 kDa

Gen-ID: 3897

UniProt: P32004

Pathways: Synaptic Membrane