SIGLEC5 Antikörper (AA 17-230)
Kurzübersicht für SIGLEC5 Antikörper (AA 17-230) (ABIN7193301)
Target
Alle SIGLEC5 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 17-230
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Verwendungszweck
- CD170 Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human CD170 (AA: 17-230) expressed in E. Coli.
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Isotyp
- IgG2a
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- SIGLEC5 (Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5))
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Andere Bezeichnung
- CD170
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Hintergrund
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This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.
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Molekulargewicht
- 60.7 kDa
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Gen-ID
- 8778
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UniProt
- O15389
Target
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