CD177 Antikörper (AA 22-161)

Produktnummer ABIN7193297

Produktdetails anti-CD177 Antikörper

Target: CD177 (CD177 Molecule (CD177))

Bindungsspezifität: AA 22-161

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD177 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), ELISA

Verwendungszweck: CD177 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human CD177 (AA: 22-161) expressed in E. Coli.

Klon: 2F2C1

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu CD177

Target: CD177 (CD177 Molecule (CD177))

Andere Bezeichnung: CD177 (CD177 Produkte)

Hintergrund:

Description:

This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified.

Aliases: NB1, PRV1, HNA2A, PRV-1, HNA-2a, NB1 GP

Molekulargewicht: 46.4kDa

Gen-ID: 57126

UniProt: Q8N6Q3