SLC8A2 Antikörper

Produktnummer ABIN7192526

Der Kaninchen Polyklonal Anti-SLC8A2-Antikörper wurde für ELISA und IHC validiert. Er ist geeignet, SLC8A2 in Proben von Human zu detektieren.

Kurzübersicht für SLC8A2 Antikörper (ABIN7192526)

Target: SLC8A2 (Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 2 (SLC8A2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC8A2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-SLC8A2 Antikörper

Kreuzreaktivität: Human, Ratte

Aufreinigung: Antigen affinity purification

Immunogen: Synthetic peptide of Human SLC8A2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA:1:1000-1:2000, IHC:1:25-1:100,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SLC8A2

Target: SLC8A2 (Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 2 (SLC8A2))

Andere Bezeichnung: SLC8A2

Hintergrund:

Background: Sodium/calcium exchanger proteins are integral membrane proteins primarily seen in cardiac cells. In cardiac myocytes, the concentration of Ca2+ alternates between low levels during relaxation and high levels during contraction. The Na+/Ca2+ exchanger 1 (NCX1) protein mediates Ca2+ extrusion from cardiac cells during relaxation. Four NCX1 isoforms (NCX1.1, NCX1.3, NCX1.7, and NCX1.10) result from alternate splicing. NCX1 mRNA is present at high levels in the heart, with lower levels present in the brain. NCX2 is most abundantly expressed in brain, in contrast the the broader distribution of NCX1, which is also expressed in heart, kidney, lung, smooth and skeletal muscle. The difference in expression for the transporter subtypes is believed to reflect differences in their functional roles. Regulation mechanisms for these exchanger proteins have not been fully characterized.

Aliases: SLC8A2 antibody, KIAA1087 antibody, NCX2 antibody, Sodium/calcium exchanger 2 antibody, Na(+)/Ca(2+)-exchange protein 2 antibody, Solute carrier family 8 member 2 antibody

UniProt: Q9UPR5