FAT4 Antikörper

Produktnummer ABIN7190632

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch FAT4 in ELISA und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für FAT4 Antikörper (ABIN7190632)

Target: FAT4 (FAT Tumor Suppressor Homolog 4 (FAT4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FAT4 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-FAT4 Antikörper

Kreuzreaktivität: Human

Aufreinigung: Antigen affinity purification

Immunogen: Synthetic peptide of Human FAT4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA:1:2000-1:5000, IHC:1:25-1:100,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu FAT4

Target: FAT4 (FAT Tumor Suppressor Homolog 4 (FAT4))

Andere Bezeichnung: FAT4

Hintergrund:

Background: FAT1, FAT2, FAT3 and FAT4 are human homologs of Drosophila Fat, which is involved in tumor suppression and planar cell polarity (PCP). FAT4 undergo the first proteolytic cleavage by Furin and are predicted to undergo the second cleavage by γ secretase to release intracellular domain (ICD). FAT4 directly interacts with MPDZ/MUPP1 to recruit membrane associated guanylate kinase MPP5/PALS1. FAT4 is involved in the maintenance of PCP and inhibition of cell proliferation.

Aliases: Cadherin family member 14 antibody, Cadherin related family member 11 antibody, CDHF14 antibody, CDHR11 antibody, FAT atypical cadherin 4 antibody, FAT J antibody, FAT tumor suppressor homolog 4 antibody, Fat-like cadherin protein FAT-J antibody, FAT4 antibody, FAT4_HUMAN antibody, FATJ antibody, hFat4 antibody, HKLLS2 antibody, Nbla00548 antibody, Protocadherin Fat 4 antibody, Putative protein product of Nbla00548 antibody, VMLDS2 antibody

UniProt: Q6V0I7