EID3 Antikörper

Produktnummer ABIN7190538

Dieses Anti-EID3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von EID3 in ELISA, IHC und WB. Geeignet für Human.

Kurzübersicht für EID3 Antikörper (ABIN7190538)

Target: EID3 (EP300 Interacting Inhibitor of Differentiation 3 (EID3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EID3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Produktdetails anti-EID3 Antikörper

Kreuzreaktivität: Human, Maus

Aufreinigung: Antigen affinity purification

Immunogen: Synthetic peptide of Human EID3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu EID3

Target: EID3 (EP300 Interacting Inhibitor of Differentiation 3 (EID3))

Andere Bezeichnung: EID3

Hintergrund:

Background: EID3 is highly expressed in testis and shows homology to a region of EID1 implicated in binding to CBP/p300. EID3 acts as a potent inhibitor of nuclear receptor transcriptional activity by a mechanism that is independent of direct interactions with nuclear receptors, including SHP. Furthermore, EID3 directly binds to and blocks the SRC-1 interacting domain of CBP, which has been implicated to act as the interaction surface for nuclear receptor co-activators. Consistent with this idea, EID3 prevents recruitment of CBP to a natural nuclear receptor-regulated promoter.

Aliases: E1A-like inhibitor of differentiation 3 antibody, EID 3 antibody, EID-1-like inhibitor of differentiation 3 antibody, EID-3 antibody, EID3 antibody, EID3_HUMAN antibody, EP300 interacting inhibitor of differentiation 3 antibody, EP300-interacting inhibitor of differentiation 3 antibody, FLJ25832 antibody, Non-SMC element 4, S. cerevisiae, homolog of, B antibody, Non-structural maintenance of chromosomes element 4 homolog B antibody, NSE4B antibody, NSMCE4B antibody

UniProt: Q8N140