ITGAV/ITGB6 Antikörper (Cy7)

Produktnummer ABIN714812

Der Kaninchen Polyklonal Anti-ITGAV/ITGB6-Antikörper wurde für FACS, WB, IF (cc) und IF (p) validiert. Er ist geeignet, ITGAV/ITGB6 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für ITGAV/ITGB6 Antikörper (Cy7) (ABIN714812)

Target: ITGAV/ITGB6 (Integrin alpha V, Integrin beta 6 (ITGAV/ITGB6))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ITGAV/ITGB6 Antikörper ist konjugiert mit Cy7

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-ITGAV/ITGB6 Antikörper (Cy7)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Integrin Alpha V + Beta 6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ITGAV/ITGB6

Target: ITGAV/ITGB6 (Integrin alpha V, Integrin beta 6 (ITGAV/ITGB6))

Andere Bezeichnung: Integrin Alpha V + Beta 6

Hintergrund:

Synonyms: CD51, Integrin alpha-V light chain, integrin, alpha V vitronectin receptor, alpha polypeptide, antigen CD51, Integrin, alpha V, Integrin, beta 6, ITAV_HUMAN, ITGAV, ITGB6, Vitronectin receptor subunit alpha.

Background: Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells. Integrin alpha-v beta-6 is upregulated in cancers and during tissue remodelling but is absent from resting adult tissues. Integrin alpha-v beta-6 promotes invasion and correlates with poor survival and therefore makes a promising therapeutic target.

Gen-ID: 36853694