AD7C-NTP Antikörper
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- Target Alle AD7C-NTP Produkte
- AD7C-NTP
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser AD7C-NTP Antikörper ist unkonjugiert
- Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Kreuzreaktivität
- Human
- Aufreinigung
- Antigen affinity purification
- Immunogen
- Synthetic peptide of Human AD7C-NTP
- Isotyp
- IgG
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anti-AD7C-NTP (N-Term) antibody
Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- ELISA:1:1000-1:5000, WB:1:200-1:1000, IHC:1:25-1:100,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- AD7C-NTP
- Abstract
- AD7C-NTP Produkte
- Hintergrund
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Background: The predicted AD7CNTP protein contains 375 amino acids and has a calculate molecular mass of about 42 kD. It is rich in serine and proline residues, has a 15-amino acid hydrophobic leader sequence, and has 7 putative membrane-spanning regions. AD7CNTP has several phosphorylation sites, a myristoylation site, and 2 serine/threonine kinase protein domains. Northern blot analysis detected 1.4- and 0.9-kb transcripts only in adult frontal and temporal lobe. In vitro studies demonstrated that overexpression of AD7CNTP in transfected neuronal cells promoted neuritic sprouting and cell death, the 2 principal neuroanatomic lesions correlated with dementia in AD.
Aliases: Neuronal thread protein AD7c-NTP
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