HES6 Antikörper (N-Term)
Kurzübersicht für HES6 Antikörper (N-Term) (ABIN7184460)
Target
Alle HES6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Kreuzreaktivität
- Human
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Synthesized peptide derived from N-terminal of Human HES6.
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Isotyp
- IgG
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Applikationshinweise
- WB:1:500-1:3000,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- HES6 (Hairy and Enhancer of Split 6 (HES6))
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Andere Bezeichnung
- HES6
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Hintergrund
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Background: Does not bind DNA itself but suppresses both HES1-mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. Also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCF3/E47, allowing ASCL1 and TCF3 to up-regulate transcription in its presence. Promotes cell differentiation By similarity. UniProtKB Q9JHE6
Bae S.-K., Development 127:2933-2943(2000).
Vasiliauskas D., Mech. Dev. 98:133-137(2000).
Ota T., Nat. Genet. 36:40-45(2004).Aliases: HES6 antibody, BHLHB41 antibody, Transcription cofactor HES-6 antibody, C-HAIRY1 antibody, Class B basic helix-loop-helix protein 41 antibody, bHLHb41 antibody, Hairy and enhancer of split 6 antibody
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UniProt
- Q96HZ4
Target
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