DOK7 Antikörper (N-Term)
Kurzübersicht für DOK7 Antikörper (N-Term) (ABIN7184448)
Target
Alle DOK7 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Kreuzreaktivität
- Human, Maus
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Synthesized peptide derived from N-terminal of Human DOK7.
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Isotyp
- IgG
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Applikationshinweise
- WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- DOK7 (Docking Protein 7 (DOK7))
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Andere Bezeichnung
- DOK7
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Hintergrund
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Background: Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis. Acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes. Induces autophosphorylation of MUSK.
Okada K., Science 312:1802-1805(2006).
Ota T., Nat. Genet. 36:40-45(2004).
Beeson D., Science 313:1975-1978(2006).Aliases: Docking protein 7 antibody, DOK 7 antibody, DOK7 antibody, DOK7_HUMAN antibody, Downstream of tyrosine kinase 7 antibody, Protein Dok-7 antibody
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UniProt
- Q18PE1
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Pathways
- Skeletal Muscle Fiber Development
Target
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