ARHGAP17 Antikörper

Produktnummer ABIN7184394

Der Kaninchen Polyklonal Anti-ARHGAP17-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, ARHGAP17 in Proben von Human zu detektieren.

Kurzübersicht für ARHGAP17 Antikörper (ABIN7184394)

Target: ARHGAP17 (rho GTPase Activating Protein 17 (ARHGAP17))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGAP17 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-ARHGAP17 Antikörper

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from internal of HumanRHG17.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:3000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ARHGAP17

Target: ARHGAP17 (rho GTPase Activating Protein 17 (ARHGAP17))

Andere Bezeichnung: ARHGAP17

Hintergrund:

Background: Rho GTPase-activating protein involved in the maintenance of tight junction by regulating the activity of CDC42, thereby playing a central role in apical polarity of epithelial cells. Specifically acts as a GTPase activator for the CDC42 GTPase by converting it to an inactive GDP-bound state. The complex formed with AMOT acts by regulating the uptake of polarity proteins at tight junctions, possibly by deciding whether tight junction transmembrane proteins are recycled back to the plasma membrane or sent elsewhere. Participates in the Ca2+-dependent regulation of exocytosis, possibly by catalyzing GTPase activity of Rho family proteins and by inducing the reorganization of the cortical actin filaments. Acts as a GTPase activator in vitro for RAC1.

Richnau N., J. Biol. Chem. 276:35060-35070(2001).
Ota T., Nat. Genet. 36:40-45(2004).
The German cDNA consortium, Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.

Aliases: ARHGAP17 antibody, RICH1 antibody, MSTP066 antibody, MSTP110 antibody, Rho GTPase-activating protein 17 antibody, Rho-type GTPase-activating protein 17 antibody, RhoGAP interacting with CIP4 homologs protein 1 antibody, RICH-1 antibody

UniProt: Q68EM7