MATK Antikörper (AA 411-507) (FITC)

Produktnummer ABIN714213

Dieses Anti-MATK-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MATK in WB, IF (cc) und IF (p). Geeignet für Human.

Kurzübersicht für MATK Antikörper (AA 411-507) (FITC) (ABIN714213)

Target: MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MATK Antikörper ist konjugiert mit FITC

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-MATK Antikörper (FITC)

Bindungsspezifität: AA 411-507

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MATK

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu MATK

Target: MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))

Andere Bezeichnung: MATK

Hintergrund:

Synonyms: CHK, Csk homologous kinase, Csk type protein tyrosine kinase, CTK, Hematopoietic consensus tyrosine lacking kinase, HHYLTK, Hydroxyaryl protein kinase, HYL, HYL tyrosine kinase, HYLTK, Leukocyte carboxyl terminal src kinase related, Lsk, Megakaryocyte associated tyrosine kinase, Megakaryocyte associated tyrosine protein kinase, Protein kinase HYL, Tyrosine kinase MATK, Tyrosine protein kinase CTK, Tyrosylprotein kinase, MATK_HUMAN.

Background: The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. MATK is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer.

Gen-ID: 4145