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TUT1 Antikörper

TUT1 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7184310
  • Target Alle TUT1 Antikörper anzeigen
    TUT1 (Terminal Uridylyl Transferase 1, U6 SnRNA-Specific (TUT1))
    Reaktivität
    • 14
    • 10
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 14
    Kaninchen
    Klonalität
    • 14
    Polyklonal
    Konjugat
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TUT1 Antikörper ist unkonjugiert
    Applikation
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Kreuzreaktivität
    Human
    Aufreinigung
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    Immunogen
    Synthesized peptide derived from internal of Human TUT1.
    Isotyp
    IgG
  • Applikationshinweise
    WB:1:500-1:3000, IHC:1:50-1:100,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    TUT1 (Terminal Uridylyl Transferase 1, U6 SnRNA-Specific (TUT1))
    Andere Bezeichnung
    TUT1 (TUT1 Produkte)
    Synonyme
    PAPD2 antikoerper, RBM21 antikoerper, STARPAP antikoerper, TUTase antikoerper, 2700038E08Rik antikoerper, Rbm21 antikoerper, zgc:112254 antikoerper, terminal uridylyl transferase 1, U6 snRNA-specific antikoerper, TUT1 antikoerper, Tut1 antikoerper, tut1 antikoerper
    Hintergrund

    Background: Poly(A) polymerase that creates the 3'-poly(A) tail of specific pre-mRNAs. Localizes to nuclear speckles together with PIP5K1A and mediates polyadenylation of a select set of mRNAs, such as HMOX1. In addition to polyadenylation, it is also required for the 3'-end cleavage of pre-mRNAs: binds to the 3'UTR of targeted pre-mRNAs and promotes the recruitment and assembly of the CPSF complex on the 3'UTR of pre-mRNAs. In addition to adenylyltransferase activity, also has uridylyltransferase activity. However, the ATP ratio is higher than UTP in cells, suggesting that it functions primarily as a poly(A) polymerase. Acts as a specific terminal uridylyltransferase for U6 snRNA in vitro: responsible for a controlled elongation reaction that results in the restoration of the four 3'-terminal UMP-residues found in newly transcribed U6 snRNA. Not involved in replication-dependent histone mRNA degradation.

    Ota T., Nat. Genet. 36:40-45(2004).
    The MGC Project Team, Genome Res. 14:2121-2127(2004).
    Trippe R.,RNA 12:1494-1504(2006).

    Aliases: alpha regulated poly(A) polymerase antibody, nuclear speckle targeted phosphatidylinositol 4 phosphate 5 kinase type I antibody, nuclear speckle targeted PIPK1A regulated poly(A) polymerase antibody, PAP associated domain containing 2 antibody, PAPD2 antibody, poly(A) polymerase associated domain containing 2 antibody, RBM21 antibody, RNA binding motif protein 21 antibody, RNA-binding motif protein 21 antibody, RNA-binding protein 21 antibody, Speckle targeted PIP5K1A-regulated poly(A) polymerase antibody, Star-PAP antibody, STARPAP antibody, STPAP_HUMAN antibody, terminal uridylyl transferase 1, U6 snRNA specific antibody, TUT1 antibody, TUTase antibody, U6 snRNA specific terminal uridylyltransferase 1 antibody, U6 snRNA-specific terminal uridylyltransferase 1 antibody, U6 TUTase antibody, U6-TUTase antibody, URLC6 antibody

    UniProt
    Q9H6E5
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