TP53INP2 Antikörper

Produktnummer ABIN7184287

Dieses Anti-TP53INP2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TP53INP2 in ELISA, IHC und IF. Geeignet für Maus.

Kurzübersicht für TP53INP2 Antikörper (ABIN7184287)

Target: TP53INP2 (Tumor Protein P53 Inducible Nuclear Protein 2 (TP53INP2))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TP53INP2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-TP53INP2 Antikörper

Kreuzreaktivität: Human, Maus

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from internal of Human TP53INP2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC:1:50-1:100, IF:1:100-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu TP53INP2

Target: TP53INP2 (Tumor Protein P53 Inducible Nuclear Protein 2 (TP53INP2))

Andere Bezeichnung: Tp53inp2

Hintergrund:

Background: Dual regulator of transcription and autophagy. Positively regulates autophagy and is required for autophagosome formation and processing. May act as a scaffold protein that recruits MAP1LC3A, GABARAP and GABARAPL2 and brings them to the autophagosome membrane by interacting with VMP1 where, in cooperation with the BECN1-PI3-kinase class III complex, they trigger autophagosome development. Acts as a transcriptional activator of THRA.

Baumgartner B.G., Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases.
Deloukas P., Nature 414:865-871(2001).
The MGC Project Team, Genome Res. 14:2121-2127(2004).

Aliases: Tp53inp2 antibody, Dor antibody, Trp53inp2 antibody, Tumor protein p53-inducible nuclear protein 2 antibody, Diabetes and obesity-regulated protein antibody

UniProt: Q8CFU8