PDZD2 Antikörper

Produktnummer ABIN7183951

Dieses Anti-PDZD2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PDZD2 in ELISA, IHC und IF. Geeignet für Human.

Kurzübersicht für PDZD2 Antikörper (ABIN7183951)

Target: PDZD2 (PDZ Domain Containing 2 (PDZD2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDZD2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-PDZD2 Antikörper

Kreuzreaktivität: Human, Maus

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from internal of Human PDZD2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC:1:50-1:100, IF:1:100-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PDZD2

Target: PDZD2 (PDZ Domain Containing 2 (PDZD2))

Andere Bezeichnung: PDZD2

Hintergrund:

Background: Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signalling. The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis.

Chaib H., Cancer Res. 61:2390-2394(2001).
Nagase T., DNA Res. 4:141-150(1997).

Aliases: PDZD2 antibody, AIPC antibody, KIAA0300 antibody, PDZK3 antibody, PDZ domain-containing protein 2 antibody, Activated in prostate cancer protein antibody, PDZ domain-containing protein 3) [Cleaved into: Processed PDZ domain-containing protein 2] antibody

UniProt: O15018