MRPS18C Antikörper

Produktnummer ABIN7183848

Der Kaninchen Polyklonal Anti-MRPS18C-Antikörper wurde für ELISA, WB, IHC und IF validiert. Er ist geeignet, MRPS18C in Proben von Human zu detektieren.

Kurzübersicht für MRPS18C Antikörper (ABIN7183848)

Target: MRPS18C (Mitochondrial Ribosomal Protein S18C (MRPS18C))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MRPS18C Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-MRPS18C Antikörper

Kreuzreaktivität: Human, Maus

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from internal of Human MRPS18C.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MRPS18C

Target: MRPS18C (Mitochondrial Ribosomal Protein S18C (MRPS18C))

Andere Bezeichnung: MRPS18C

Hintergrund:

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. Pseudogenes corresponding to this gene are found on chromosomes 8p, 12p, 15q, and 22q.

Lai C.-H., Genome Res. 10:703-713(2000).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Koc E.C., J. Biol. Chem. 276:19363-19374(2001).

Aliases: MRPS18C antibody, CGI-134 antibody, 28S ribosomal protein S18c antibody, mitochondrial antibody, MRP-S18-c antibody, Mrps18-c antibody, S18mt-c antibody, 28S ribosomal protein S18-1 antibody, mitochondrial antibody, MRP-S18-1 antibody, Mitochondrial small ribosomal subunit protein bS18c antibody, Mitochondrial small ribosomal subunit protein bS18m antibody

UniProt: Q9Y3D5