MARK2 Antikörper (pSer595) (Cy7)
Kurzübersicht für MARK2 Antikörper (pSer595) (Cy7) (ABIN714077)
Target
Alle MARK2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer595
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Kreuzreaktivität
- Human, Maus, Ratte
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic phosphopeptide derived from human MARK2 around the phosphorylation site of Ser595
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Isotyp
- IgG
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Applikationshinweise
- IF(IHC-P)(1:50-200)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- MARK2 (MAP/microtubule Affinity-Regulating Kinase 2 (MARK2))
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Andere Bezeichnung
- Mark2
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Hintergrund
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Synonyms: ELKL mot kinase 1, MARK2phospho S595, ELKL mot kinase, EMK-1, EMK1, MAP/microtubule affinity regulating kinase 2, MAP/microtubule affinity-regulating kinase 2, Mark2, MARK2_HUMAN, PAR1 homolog, Serine/threonine protein kinase MARK2, Serine/threonine-protein kinase MARK2.
Background: MARK2 refers to MAP/microtubule affinity-regulating kinase 2 isoform a [Homo sapiens]. EMK (ELKL Motif Kinase) is a small family of ser/thr protein kinases involved in the control of cell polarity, microtubule.stability and cancer. Several cDNA clones have been isolated that encoded two isoforms of the human ser/thr protein kinase EMK1 called MARK2. These isoforms were characterized by the presence of a 162-bp alternative exon that gave rise to two forms, one containing the exon and the other one lacking it. Both forms were found to be coexpressed in a number of selected cell lines and tissue samples. Human MARK2 was shown to be encoded by a single mRNA ubiquitously expressed. This transcription variant includes the alternative exon in the coding region and therefore codes for a longer protein. Multiple splice variants exist for this protein.
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Gen-ID
- 2011
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UniProt
- Q7KZI7
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Pathways
- SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion
Target
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