GUCY1B3 Antikörper

Produktnummer ABIN7181380

Dieses Anti-GUCY1B3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GUCY1B3 in WB, ELISA, IHC und IF. Geeignet für Human.

Kurzübersicht für GUCY1B3 Antikörper (ABIN7181380)

Target: GUCY1B3 (Guanylate Cyclase 1, Soluble, beta 3 (GUCY1B3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GUCY1B3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-GUCY1B3 Antikörper

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from Human Guanylate Cyclase beta.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:3000, IHC:1:50-1:200, IF:1:100-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu GUCY1B3

Target: GUCY1B3 (Guanylate Cyclase 1, Soluble, beta 3 (GUCY1B3))

Andere Bezeichnung: GUCY1B1

Hintergrund:

Background: This gene encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate). The encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants.

A. Shimouchi, Am J Physiol Lung Cell Mol Physiol, Nov 1993, 265: 456.
Peter Sinnaeve, Circ. Res., Jan 2001, 88: 103.
Stephan Thelitz, J. Thorac. Cardiovasc. Surg., May 2004, 127: 1285 - 1292.
Richard C. Venema, Am J Physiol Heart Circ Physiol, Jul 2003, 2

Aliases: GC-S-beta-1 antibody, GC-SB3 antibody, GCbeta1 antibody, GCS beta 1 antibody, GCS beta 3 antibody, GCS-beta-1 antibody, GCS-beta-3 antibody, GCYB1_HUMAN antibody, guanylate cyclase 1, soluble, beta 3 antibody, Guanylate cyclase soluble beta 1 chain antibody, Guanylate cyclase soluble subunit beta-1 antibody, Guanylate cyclase soluble subunit beta-3 antibody, GUC1B3 antibody, GUCSB3 antibody, GUCY1B1 antibody, Gucy1b1, antibody, GUCY1B3 antibody, SGC antibody, Soluble guanylate cyclase small subunit antibody

UniProt: Q02153

Pathways: Transition Metal Ion Homeostasis