Thrombomodulin Antikörper (C-Term)
Kurzübersicht für Thrombomodulin Antikörper (C-Term) (ABIN7180265)
Target
Alle Thrombomodulin (THBD) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Kreuzreaktivität
- Human
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Synthesized peptide derived from C-terminal of Human THBD.
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Isotyp
- IgG
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Applikationshinweise
- WB:1:500-1:3000,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Thrombomodulin (THBD)
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Andere Bezeichnung
- THBD
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Hintergrund
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Background: Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.
Suzuki K., EMBO J. 6:1891-1897(1987).
Wen D., Biochemistry 26:4350-4357(1987). Jackman R.W., Proc. Natl. Acad. Sci. U.S.A. 84:6425-6429(1987).Aliases: AHUS 6 antibody, AHUS6 antibody, BDCA 3 antibody, BDCA3 antibody, CD 141 antibody, CD141 antibody, CD141 antigen antibody, Fetomodulin antibody, Thbd antibody, THPH12 antibody, THRM antibody, Thrombomodulin antibody, TM antibody, TRBM_HUMAN antibody
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UniProt
- P07204
Target
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