Pre-mRNA Branch Site Protein p14 (SF3B14) (C-Term) Antikörper
Kurzübersicht für Pre-mRNA Branch Site Protein p14 (SF3B14) (C-Term) Antikörper (ABIN7180242)
Target
Alle Pre-mRNA Branch Site Protein p14 (SF3B14) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Kreuzreaktivität
- Human, Maus
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Synthesized peptide derived from C-terminal of Human SF3B14.
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Isotyp
- IgG
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Applikationshinweise
- WB:1:500-1:3000,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Pre-mRNA Branch Site Protein p14 (SF3B14)
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Andere Bezeichnung
- SF3B6
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Hintergrund
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Background: Necessary for the splicing of pre-mRNA. Directly contacts the pre-mRNA branch site adenosine for the first catalytic step of splicing. Enters the spliceosome and associates with the pre-mRNA branch site as part of the 17S U2 or, in the case of the minor spliceosome, as part of the 18S U11/U12 snRNP complex, and thus may facilitate the interaction of these snRNP with the branch sites of U2 and U12 respectively.
Will C.L., EMBO J. 20:4536-4546(2001).
Lai C.-H., Genome Res. 10:703-713(2000).
Zhang Q.-H., Genome Res. 10:1546-1560(2000).Aliases: Ht006 antibody, P14 antibody, PM14_HUMAN antibody, Pre mRNA branch site protein p14 antibody, Pre-mRNA branch site protein p14 antibody, SAP14 antibody, SF3B 14 kDa subunit antibody, SF3B14 antibody, SF3B14a antibody, Splicing factor 3B, 14 kDa subunit antibody
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UniProt
- Q9Y3B4
Target
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