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NDFIP1 Antikörper (C-Term)

NDFIP1 Reaktivität: Human ELISA, WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7180214
  • Target Alle NDFIP1 Antikörper anzeigen
    NDFIP1 (Nedd4 Family Interacting Protein 1 (NDFIP1))
    Bindungsspezifität
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 39
    • 15
    • 10
    Human
    Wirt
    • 37
    • 3
    • 1
    • 1
    Kaninchen
    Klonalität
    • 39
    • 3
    Polyklonal
    Konjugat
    • 16
    • 5
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NDFIP1 Antikörper ist unkonjugiert
    Applikation
    • 24
    • 23
    • 8
    • 5
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB)
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    Immunogen
    Synthesized peptide derived from C-terminal of Human NDFIP1.
    Isotyp
    IgG
    Top Product
    Discover our top product NDFIP1 Primärantikörper
  • Applikationshinweise
    WB:1:500-1:3000,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    NDFIP1 (Nedd4 Family Interacting Protein 1 (NDFIP1))
    Andere Bezeichnung
    NDFIP1 (NDFIP1 Produkte)
    Synonyme
    zgc:55546 antikoerper, wu:fc17e11 antikoerper, n4wbp5 antikoerper, MGC108163 antikoerper, ndfip1 antikoerper, NDFIP1 antikoerper, N4WBP5 antikoerper, 0610010M22Rik antikoerper, N4wbp5 antikoerper, Nedd4 family interacting protein 1 antikoerper, Nedd4 WW domain-binding protein 5 antikoerper, ndfip1 antikoerper, NDFIP1 antikoerper, n4wbp5 antikoerper, Ndfip1 antikoerper
    Hintergrund

    Background: Activates HECT domain-containing E3 ubiquitin-protein ligases, including NEDD4 and ITCH, and consequently modulates the stability of their targets. As a result, controls many cellular processes. Prevents chronic T-helper cells-mediated inflammation by activating ITCH and thus controlling JUNB degradation By similarity. In cortical neurons, mediates the ubiquitination of SLC11A2/DMT1 by NEDD4L, leading to down-regulation of the divalent metal transporter and protection of the cells from cobalt and iron toxicity. Modulates EGFR signaling through multiple pathways. In particular, may regulate the ratio of AKT1-to-MAPK8 signaling in response to EGF, acting on AKT1 probably through PTEN destabilization and on MAPK8 through ITCH-dependent MAP2K4 inactivation. As a result, may control cell growth rate.

    Petroziello J.M., Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases.
    Matsuda A., Oncogene 22:3307-3318(2003).
    Otsuki T., DNA Res. 12:117-126(2005).

    Aliases: 0610010M22Rik antibody, Breast cancer associated protein SGA 1M antibody, Breast cancer-associated protein SGA-1M antibody, MGC10924 antibody, N4WBP5 antibody, Ndfip1 antibody, Nedd4 family interacting protein 1 antibody, NEDD4 family-interacting protein 1 antibody, NEDD4 WW domain binding protein 5 antibody, NEDD4 WW domain-binding protein 5 antibody, NFIP1_HUMAN antibody, Putative MAPK activating protein PM13 antibody, Putative MAPK-activating protein PM13 antibody, Putative NF kappa B activating protein 164 antibody, Putative NF-kappa-B-activating protein 164 antibody, Putative NFKB and MAPK activating protein antibody, Putative NFKB and MAPK-activating protein antibody

    UniProt
    Q9BT67
    Pathways
    Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Negative Regulation of Transporter Activity
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