GNE Antikörper (C-Term)

Produktnummer ABIN7180179

Der Kaninchen Polyklonal Anti-GNE-Antikörper wurde für WB, IHC und ELISA validiert. Er ist geeignet, GNE in Proben von Human zu detektieren.

Kurzübersicht für GNE Antikörper (C-Term) (ABIN7180179)

Target: GNE (Glucosamine (UDP-N-Acetyl)-2-Epimerase/N-Acetylmannosamine Kinase (GNE))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GNE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-GNE Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität: Human

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from C-terminal of Human GNE.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:3000, IHC:1:50-1:100,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu GNE

Target: GNE (Glucosamine (UDP-N-Acetyl)-2-Epimerase/N-Acetylmannosamine Kinase (GNE))

Andere Bezeichnung: GNE

Hintergrund:

Background: Regulates and initiates biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. Plays an essential role in early development By similarity. Required for normal sialylation in hematopoietic cells. Sialylation is implicated in cell adhesion, signal transduction, tumorigenicity and metastatic behavior of malignant cells.

Lucka L., FEBS Lett. 454:341-344(1999).
Seppala R., Am. J. Hum. Genet. 64:1563-1569(1999).
Huizing M., Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases.

Aliases: 2310066H07Rik antibody, Bifunctional UDP N acetylglucosamine 2 epimerase/N acetylmannosamine kinase antibody, DMRV antibody, GLCNE_HUMAN antibody, Glucosamine (UDP N acetyl) 2 epimerase/N acetylmannosamine kinase antibody, GNE antibody, IBM2 antibody, ManAc kinase antibody, N acylmannosamine kinase antibody, N-acetylmannosamine kinase antibody, NM antibody, RP23-209M8.6 antibody, Uae1 antibody, UDP GlcNAc 2 epimerase antibody, UDP GlcNAc 2 epimerase/ManAc kinase antibody, UDP N acetylglucosamine 2 epimerase/N acetylmannosamine kinase antibody, UDP-GlcNAc-2-epimerase antibody, UDP-GlcNAc-2-epimerase/ManAc kinase antibody, Uridine diphosphate N acetylglucosamine 2 epimerase antibody, Uridine diphosphate-N-acetylglucosamine-2-epimerase antibody

UniProt: Q9Y223