Mps1 Antikörper (Thr676)

Produktnummer ABIN7180102

Dieses Anti-Mps1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Mps1 in WB, ELISA und IHC. Geeignet für Human.

Kurzübersicht für Mps1 Antikörper (Thr676) (ABIN7180102)

Target: Mps1 (TTK)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Mps1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-Mps1 Antikörper

Bindungsspezifität: Thr676

Kreuzreaktivität: Human, Maus

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized non-phosphopeptide derived from Human TTK around the phosphorylation site of threonine 676 (D-T-T(p)-S-V).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:3000, IHC:1:50-1:100,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Mps1

Target: Mps1 (TTK)

Andere Bezeichnung: TTK

Hintergrund:

Background: Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint.

Mills G.B., J. Biol. Chem. 267:16000-16006(1992).
Ota T., Nat. Genet. 36:40-45(2004).
Mungall A.J., Nature 425:805-811(2003)

Aliases: cancer/testis antigen 96 antibody, CT96 antibody, Dual specificity protein kinase TTK antibody, ECSTY kinase antibody, ESK antibody, FLJ38280 antibody, hMPS1 antibody, Monopolar Spindle 1 Like 1 antibody, MPH1 antibody, Mps 1 antibody, MPS1L1 antibody, Phosphotyrosine Picked Threonine Kinase antibody, Phosphotyrosine picked threonine-protein kinase antibody, PYT antibody, RP3-357D13.2 antibody, ttk antibody, TTK Protein Kinase antibody, TTK_HUMAN antibody

UniProt: P33981