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MBNL3 Antikörper (AA 251-354)

Der Kaninchen Polyklonal Anti-MBNL3-Antikörper wurde für ELISA, WB, IF (cc), IF (p), IHC (fro) und IHC (p) validiert. Er ist geeignet, MBNL3 in Proben von Maus zu detektieren.
Produktnummer ABIN713756

Kurzübersicht für MBNL3 Antikörper (AA 251-354) (ABIN713756)

Target

Alle MBNL3 Antikörper anzeigen
MBNL3 (Muscleblind-Like Splicing Regulator 3 (MBNL3))

Reaktivität

  • 26
  • 1
Maus

Wirt

  • 24
  • 2
Kaninchen

Klonalität

  • 25
  • 1
Polyklonal

Konjugat

  • 12
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser MBNL3 Antikörper ist unkonjugiert

Applikation

  • 14
  • 12
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Bindungsspezifität

    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 251-354

    Kreuzreaktivität

    Maus

    Homologie

    Human,Rat,Cow,Sheep,Pig,Horse

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human MBNL3

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Haltbarkeit

    12 months
  • Target

    MBNL3 (Muscleblind-Like Splicing Regulator 3 (MBNL3))

    Andere Bezeichnung

    MBNL3

    Hintergrund

    Synonyms: MBLX, CHCR, Cys3His CCG1 required protein, MBLX39, MBNL 3, MBXL, Muscleblind like protein 3, Muscleblind like X linked protein, Protein HCHCR, MBNL3_HUMAN.

    Background: MBNL3 has been shown to inhibit muscle differentiation. MBNL3 belongs to a highly conserved family of tissue-specific alternative splicing regulators. This family is known to regulate terminal muscle differentiation through alternative splicing control and several groups have suggested that the family participates in the differentiation of photoreceptors, neurons, adipocytes and blood cell types. MBNL3 is expressed in myoblasts, muscle precursor cells, and during the early stages of myogenesis, but is detected at very low levels in terminally differentiated myotubes. MBNL proteins have been shown to sequester foci of expanded-repeat transcripts and are thought to therefore play a role in the molecular pathology of a group of neuromuscular diseases including the Myotonic Dystrophies.

    Gen-ID

    55796

    UniProt

    Q9NUK0

    Pathways

    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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