SRI Antikörper (AA 32-116) (Biotin)
Kurzübersicht für SRI Antikörper (AA 32-116) (Biotin) (ABIN7179480)
Target
Alle SRI Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 32-116
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Kreuzreaktivität
- Staphylococcus aureus
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Staphylococcus aureus Staphylococcal complement inhibitor protein (32-116AA)
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Isotyp
- IgG
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anti-Sorcin (SRI) (AA 1-198) antibody
SRI Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Sorcin (SRI) (AA 1-198) antibodySRI Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 1E12 unconjugated
anti-Sorcin (SRI) (AA 1-198) antibodySRI Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Sorcin (SRI) antibodyKO Validated SRI Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Sorcin (SRI) (AA 29-169) antibodySRI Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Sorcin (SRI) (C-Term) antibodySRI Reaktivität: Human, Ratte, Pferd, Hund, Rind (Kuh), Schaf, Affe, Schwein WB Wirt: Kaninchen Polyclonal unconjugated
anti-Sorcin (SRI) (AA 96-145) antibodySRI Reaktivität: Human, Kaninchen, Affe WB Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SRI (Sorcin (SRI))
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Andere Bezeichnung
- scn
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Hintergrund
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Background: Involved in countering the first line of host defense mechanisms. Efficiently inhibits opsonization, phagocytosis and killing of S.aureus by human neutrophils. Acts by binding and stabilizing human C3 convertases (C4b2a and C3bBb), leading to their inactivation. The convertases are no longer able to cleave complement C3, therefore preventing further C3b deposition on the bacterial surface and phagocytosis of the bacterium. Also prevents C5a-induced neutrophil responses.
Aliases: scn antibody, SA1754 antibody, Staphylococcal complement inhibitor antibody, SCIN antibody
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UniProt
- Q99SU9
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Pathways
- Transition Metal Ion Homeostasis, Maintenance of Protein Location, Negative Regulation of Transporter Activity
Target
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