TIMP1 Antikörper (AA 24-217) (FITC)

Produktnummer ABIN7178943

Der Kaninchen Polyklonal Anti-TIMP1-Antikörper wurde für validiert. Er ist geeignet, TIMP1 in Proben von Ratte zu detektieren.

Kurzübersicht für TIMP1 Antikörper (AA 24-217) (FITC) (ABIN7178943)

Target: TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TIMP1 Antikörper ist konjugiert mit FITC

Applikation: Bitte anfragen

Produktdetails anti-TIMP1 Antikörper (FITC)

Bindungsspezifität: AA 24-217

Kreuzreaktivität: Ratte

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Rat Metalloproteinase inhibitor 1 protein (24-217AA)

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu TIMP1

Target: TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

Andere Bezeichnung: Timp1

Hintergrund:

Background: Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Also stimulates steroidogenesis by Leydig and ovarian granuloma cells, procathepsin L is required for maximal activity.

Aliases: Timp1 antibody, Timp-1 antibody, Metalloproteinase inhibitor 1 antibody, Tissue inhibitor of metalloproteinases 1 antibody, TIMP-1 antibody

UniProt: P30120