DPH1 Antikörper (AA 251-350) (Biotin)

Produktnummer ABIN713653

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch DPH1 in WB, ELISA, IHC (fro) und IHC (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für DPH1 Antikörper (AA 251-350) (Biotin) (ABIN713653)

Target: DPH1 (DPH1 Homolog (DPH1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DPH1 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-DPH1 Antikörper (Biotin)

Bindungsspezifität: AA 251-350

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Cow,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human OVCA1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu DPH1

Target: DPH1 (DPH1 Homolog (DPH1))

Andere Bezeichnung: OVCA1

Hintergrund:

Synonyms: Candidate tumor suppressor in ovarian cancer 1, Diphthamide biosynthesis protein 1, Diphthamide biosynthesis protein 2 homolog like 1, Diphthamide biosynthesis protein 2 like, Diptheria toxin resistance protein required for diphthamide biosynthesis Saccharomyces like 1 , Diptheria toxin resistance protein required for diphthamide biosynthesis like 1, DPH like 1 S. cerevisiae, DPH like 1, DPH1, DPH1 homolog S. cerevisiae, DPH1 homolog, DPH2 like 1, DPH2L, DPH2L1, HsDph1, Ovarian cancer associated gene 1, Ovarian cancer associated gene 1 protein, Ovarian tumor suppressor candidate 1, DPH1_HUMAN.

Background: OVCA1 is required for the first step in the synthesis of diphthamide, a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2, MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. OVCA1 is one of several enzymes involved in synthesis of diphthamide in EEF2.

Gen-ID: 1801