CD163 Antikörper (AA 86-365) (FITC)
Kurzübersicht für CD163 Antikörper (AA 86-365) (FITC) (ABIN7177828)
Target
Alle CD163 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
 - AA 86-365
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Kreuzreaktivität
 - Maus
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Aufreinigung
 - >95%, Protein G purified
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Immunogen
 - Recombinant Mouse Scavenger receptor cysteine-rich type 1 protein M130 protein (86-365AA)
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Isotyp
 - IgG
 
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Beschränkungen
 - Nur für Forschungszwecke einsetzbar
 
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Format
 - Liquid
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Buffer
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                        Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 
                                            
Konservierungsmittel
 - ProClin
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Vorsichtsmaßnahmen
 - This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
 - -20 °C,-80 °C
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Informationen zur Lagerung
 - Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
 
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- CD163
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Andere Bezeichnung
 - Cd163
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Hintergrund
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Background: Involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH -dependent manner. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1 (By similarity).
Aliases: Cd163 antibody, M130Scavenger receptor cysteine-rich type 1 protein M130 antibody, CD antigen CD163) [Cleaved into: Soluble CD163 antibody, sCD163)] antibody
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UniProt
 - Q2VLH6
 
Target
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