KEAP1 Antikörper (AA 1-624) (Biotin)
Kurzübersicht für KEAP1 Antikörper (AA 1-624) (Biotin) (ABIN7177370)
Target
Alle KEAP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-624
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Kreuzreaktivität
- Maus
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Mouse Kelch-like ECH-associated protein 1 protein (1-624AA)
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Isotyp
- IgG
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anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 325-624) antibody
KEAP1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 380-624) antibodyKEAP1 Reaktivität: Human, Maus ELISA, ICC, FACS Wirt: Maus Monoclonal 1F10B6 unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 380-624) antibodyKEAP1 Reaktivität: Human ELISA, IHC, FACS Wirt: Maus Monoclonal 7G4B10 unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) antibodyKEAP1 Reaktivität: Human, Maus WB, IHC, IHC (p), FACS Wirt: Maus Monoclonal 1B4 unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 380-624) antibodyKEAP1 Reaktivität: Human WB, ELISA, IHC, FACS Wirt: Maus Monoclonal unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (C-Term) antibodyKEAP1 Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Pferd, Meerschweinchen, Zebrafisch (Danio rerio) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 327-624) antibodyKEAP1 Reaktivität: Human WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 1-286) antibodyKEAP1 Reaktivität: Maus WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 65-160) antibodyKEAP1 Reaktivität: Human, Maus, Ratte, Schwein, Kaninchen WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 41-53) antibodyVerified KEAP1 Reaktivität: Human ELISA, IHC, IF Wirt: Ziege Polyclonal unconjugated
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))
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Andere Bezeichnung
- Keap1
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Hintergrund
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Background: Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome (By similarity).
Aliases: Keap1 antibody, Inrf2 antibody, Kiaa0132Kelch-like ECH-associated protein 1 antibody, Cytosolic inhibitor of Nrf2 antibody, INrf2 antibody
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UniProt
- Q9Z2X8
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Pathways
- Maintenance of Protein Location
Target
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