IRF8 Antikörper (AA 1-424) (Biotin)
Kurzübersicht für IRF8 Antikörper (AA 1-424) (Biotin) (ABIN7177346)
Target
Alle IRF8 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-424
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Kreuzreaktivität
- Maus
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Mouse Interferon regulatory factor 8 protein (1-424AA)
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- IRF8 (Interferon Regulatory Factor 8 (IRF8))
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Andere Bezeichnung
- Irf8
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Hintergrund
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Background: Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)). Plays a regulatory role in cells of the immune system. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5\'-TGAnTCA/GAAA-3\'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF8 and activation of genes.
Aliases: Irf8 antibody, Icsbp antibody, Icsbp1 antibody, Interferon regulatory factor 8 antibody, IRF-8 antibody, Interferon consensus sequence-binding protein antibody, ICSBP antibody
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UniProt
- P23611
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Pathways
- Cellular Response to Molecule of Bacterial Origin
Target
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