WAC Antikörper (AA 10-102) (HRP)

Produktnummer ABIN7175870

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch WAC in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für WAC Antikörper (AA 10-102) (HRP) (ABIN7175870)

Target: WAC (WW Domain Containing Adaptor with Coiled-Coil (WAC))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WAC Antikörper ist konjugiert mit HRP

Applikation: ELISA

Produktdetails anti-WAC Antikörper (HRP)

Bindungsspezifität: AA 10-102

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human WW domain-containing adapter protein with coiled-coil protein (10-102AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu WAC

Target: WAC (WW Domain Containing Adaptor with Coiled-Coil (WAC))

Andere Bezeichnung: WAC

Hintergrund:

Background: Acts as a linker between gene transcription and histone H2B monoubiquitination at \\\'Lys-120\\\' (H2BK120ub1). Interacts with the RNA polymerase II transcriptional machinery via its WW domain and with RNF20-RNF40 via its coiled coil region, thereby linking and regulating H2BK120ub1 and gene transcription. Regulates the cell-cycle checkpoint activation in response to DNA damage. Positive regulator of amino acid starvation-induced autophagy. May negatively regulate the ubiquitin proteasome pathway.

Aliases: 1110067P07Rik antibody, BA48B24 antibody, BA48B24.1 antibody, BM 016 antibody, FLJ31290 antibody, KIAA1844 antibody, MGC10753 antibody, OTTHUMP00000019380 antibody, OTTHUMP00000019382 antibody, PRO1741 antibody, wac antibody, WAC_HUMAN antibody, WW domain containing adapter protein with coiled coil antibody, WW domain containing adaptor with coiled coil antibody, WW domain-containing adapter protein with coiled-coil antibody, Wwp4 antibody

UniProt: Q9BTA9

Pathways: Chromatin Binding