WT1 Antikörper (AA 1-449)
Kurzübersicht für WT1 Antikörper (AA 1-449) (ABIN7175818)
Target
Alle WT1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-449
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Kreuzreaktivität
- Human
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human Wilms tumor protein (1-449AA)
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: IHC:1:20-1:200,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- WT1 (Wilms Tumor 1 (WT1))
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Andere Bezeichnung
- WT1
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Hintergrund
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Background: Transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5\'-CGCCCCCGC-3\'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA.
Aliases: WIT 2 antibody, WT 1 antibody, AWT1 antibody, FWT1 antibody, GUD antibody, NPHS4 antibody, WAGR antibody, Wilms tumor 1 antibody, Wilms Tumor antibody, Wilms tumor protein antibody, Wilms' tumor gene antibody, Wilms' tumor protein antibody, WIT2 antibody, WT antibody, WT1 antibody, WT1_HUMAN antibody, WT33 antibody
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UniProt
- P19544
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Pathways
- Tube Formation
Target
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