WDR41 Antikörper (AA 7-284) (HRP)

Produktnummer ABIN7175754

Produktdetails anti-WDR41 Antikörper (HRP)

Target: WDR41 (WD Repeat Domain 41 (WDR41))

Bindungsspezifität: AA 7-284

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WDR41 Antikörper ist konjugiert mit HRP

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human WD repeat-containing protein 41 protein (7-284AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu WDR41

Target: WDR41 (WD Repeat Domain 41 (WDR41))

Andere Bezeichnung: WDR41 (WDR41 Produkte)

Synonyme: WDR41 antikoerper, MGC142930 antikoerper, wdr41 antikoerper, fj48d04 antikoerper, wu:fj48d04 antikoerper, zgc:110041 antikoerper, B830029I03Rik antikoerper, MSTP048 antikoerper, WD repeat domain 41 antikoerper, Wdr41 antikoerper, WDR41 antikoerper, wdr41 antikoerper

Hintergrund:

Background: Non-catalytic component of the C9orf72-SMCR8 complex, a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy (PubMed:27193190, PubMed:27103069, PubMed:27617292, PubMed:28195531). The C9orf72-SMCR8 complex promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB8A and RAB39B into their active GTP-bound form, thereby promoting autophagosome maturation (PubMed:27103069). The C9orf72-SMCR8 complex also acts as a negative regulator of autophagy initiation by interacting with the ATG1/ULK1 kinase complex and inhibiting its protein kinase activity (PubMed:27103069, PubMed:27617292).

Aliases: FLJ10904 antibody, MSTP048 antibody, WD repeat domain 41 antibody, WD repeat protein 41 antibody, WD repeat-containing protein 41 antibody, WDR 41 antibody, WDR41 antibody, WDR41_HUMAN antibody

UniProt: Q9HAD4